Created by: karen.west
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Reconstitution of tissue by functional incorporation of transplanted stem-cell progeny. Distinct from 'bystander' trophic, anti-inflammatory or immunomodulatory effects of introduced cells.
A population of cells all carrying the same genes, grown in the laboratory through many cycles of growth and division over many generations of cells.
Cell that can produce a new cancer upon transplantation. A key property of a cancer stem cell.
The growth of cells in a laboratory dish for experimental research. The cells are grown in a solution, or medium, that contains nutrients and growth factors. Different factors can be added to the ...
Self-renewing cell responsible for sustaining a cancer and for producing differentiated progeny that form the bulk of the cancer. Cancer stem cells identified in leukaemias and certain solid tumours ...
Cell division resulting in two daughter cells with different properties. Observed in some but not all stem cells and can occur in other types of progenitor cell.
An early stage embryo of about 100 cells that has not yet implanted into the womb. The blastocyst is a sphere made up of an outer layer of cells, a fluid-filled cavity and cluster of cells inside ...