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The position on a chromosome of a gene or other chromosome marker; also, the DNA at that position. The use of locus is sometimes restricted to mean expressed DNA regions.
See also: gene expression.
Industry:Biology
Restriction enzymes are proteins that cut DNA at precise locations. Restriction maps depict the chromosomal positions of restriction-enzyme cutting sites. These are used as biochemical "signposts," or markers of specific areas along the chromosomes. The map will detail the positions where the DNA molecule is cut by particular restriction enzymes.
Industry:Biology
An exact copy made of biological material such as a DNA segment (e.g., a gene or other region), a whole cell, or a complete organism..
Industry:Biology
A process whereby the order of multiple sequenced DNA fragments is determined..
Industry:Biology
Map depicting the order of and distance between sites at which restriction enzymes cleave chromosomes..
Industry:Biology
Short (200 to 500 base pairs) DNA sequence that has a single occurrence in the human genome and whose location and base sequence are known. Detectable by polymerase chain reaction, STSs are useful for localizing and orienting the mapping and sequence data reported from many different laboratories and serve as landmarks on the developing physical map of the human genome. Expressed sequence tags (ESTs) are STSs derived from cDNAs..
Industry:Biology
