Home > Term: Ames test
Ames test
In vitro test for mutagenicity using mutant strains of the bacterium Salmonella typhimurium which cannot grow in a given histidine-deficient medium: mutagens can cause reverse mutations which enable the bacterium to grow on the medium. The test can be carried out in the presence of a given microsomal fraction (S-9) from rat liver (see microsome) to allow metabolic transformation of mutagen precursors to active derivatives.
- Jenis Kata: noun
- Industri / Domain: Biologi; Bahan-bahan kimia
- Kategori: Ilmu tentang racun
- Company: National Library of Medicine
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Penulis
- Walter Lane
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