Capital of the dep. of Vaucluse, France; an ancient city beautifully situated on the left bank of the Rhône, near the confluence of the Durance, of various fortune from its foundation by the Phocaeans in 539 B.C.; was the seat of the Papacy from 1305 to 1377, purchased by Pope Clement VI. at that period, and belonged to the Papacy from that time till 1797, when it was appropriated to France; it contains a number of interesting buildings, and carries on a large trade in wine, oil, and fruits; grows and manufactures silk in large quantities.