Home >  Term: denaturing gradient gel electrophoresis (DGGE)
denaturing gradient gel electrophoresis (DGGE)

Identification of mutations by electrophoresis of double-stranded DNA samples through a denaturing gradient, such as urea. Certain mutations affect the migration pattern by changing the point in the gel at which the DNA denatures; mutant sequences can be distinguished from wild-type sequences by comparing the electrophoretic pattern.

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