Home >  Term: in situ hybridization
in situ hybridization

A technique used for hybridization of cytological (chromosome) preparations with the labeled DNA probes. The method couples molecular biology, biochemistry, and cytology. Usually the expression of a gene (as RNA) or the location of target DNA (for example, in a chromosome) is detected by a molecular probe. The probe can be labeled by a variety of biochemical methods.

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