Home > Term: kernicterus
kernicterus
A term used pathologically to describe bilirubin staining of the basal ganglia; brain stem; and cerebellum and clinically to describe a syndrome associated with hyperbilirubinemia. Clinical features include athetosis, muscle spasticity or hypotonia, impaired vertical gaze, and deafness. Nonconjugated bilirubin enters the brain and acts as a neurotoxin, often in association with conditions that impair the blood-brain barrier (e.g., sepsis). This condition occurs primarily in neonates (newborn infant), but may rarely occur in adults.
- Jenis Kata: noun
- Industri / Domain: Medis; Perawatan kesehatan
- Kategori: Pengobatan
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(Canada)