Home >  Term: zig-zag DNA (Z-DNA)
zig-zag DNA (Z-DNA)

A form of DNA duplex in which the double helix is wound in a left-hand, instead of a right-hand, manner. DNA adopts the Z configuration when purines and pyrimidines alternate on a single strand, e.g.,

5´CGCGCGCG3´ or 5´CACACACACA3´

3´GCGCGCGC5´ 3´GTGTGTGTGT5´

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